Protein XPA map

Identifiers
xeroderma pigmentosum, complementation group A
HUGO:XPA, HGNC:12814, ENTREZ:7507, UNIPROT:P23025

Maps_Modules
HMC:GENOME_INSTABILITY_AND_MUTATION
 Cell Cycle DNA Repair  map  / NER  map

References
PMID:22373527, PMID:23085398, PMID:22824526, PMID:22373527, PMID:22257761
PMID:19809470 PMID:15703371, PMID:19847258, PMID:16697054, PMID:12648680, PMID:17884153, PMID:11900249

XPA|​S196_pho@Nucleus

References
ce_re235( Cell Cycle DNA Repair  map ):
ATR phosphorylates XPA and activates NER during S-phase in response to damaged DNA, but not during other cc phases:
PMID:16540648, PMID:19004803

XPA@Nucleus

References
ce_re235( Cell Cycle DNA Repair  map ):
ATR phosphorylates XPA and activates NER during S-phase in response to damaged DNA, but not during other cc phases:
PMID:16540648, PMID:19004803

Modifications:
In compartment: Nucleus
  1. XPA@Nucleus map
  2. XPA|​S196_pho@Nucleus map
Participates in complexes:
In compartment: Nucleus
  1. XAB2:​XPA|​S196_pho@Nucleus map
  2. CDK7:​CyclinH*:​MNAT1:​RPA2|​pho:​TFIIH1*:​TFIIH2*:​TFIIH3*:​TFIIH4*:​TFIIH5*:​XAB2:​XPA|​S196_pho:​XPB*:​XPD*@Nucleus map
  3. CDK7:​CyclinH*:​ERCC1:​MNAT1:​RPA2|​pho:​TFIIH1*:​TFIIH2*:​TFIIH3*:​TFIIH4*:​TFIIH5*:​XAB2:​XPA|​S196_pho:​XPB*:​XPD*:​XPF*:​XPG*@Nucleus map
Participates in reactions:
As Reactant or Product:
  1. CDK7:​CyclinH*:​MNAT1:​TFIIH1*:​TFIIH2*:​TFIIH3*:​TFIIH4*:​TFIIH5*:​XPB*:​XPD*@Nucleus map + ce_s3289 + XAB2:​XPA|​S196_pho@Nucleus map → map CDK7:​CyclinH*:​MNAT1:​RPA2|​pho:​TFIIH1*:​TFIIH2*:​TFIIH3*:​TFIIH4*:​TFIIH5*:​XAB2:​XPA|​S196_pho:​XPB*:​XPD*@Nucleus map
  2. CDK7:​CyclinH*:​MNAT1:​RPA2|​pho:​TFIIH1*:​TFIIH2*:​TFIIH3*:​TFIIH4*:​TFIIH5*:​XAB2:​XPA|​S196_pho:​XPB*:​XPD*@Nucleus map + ERCC1@Nucleus map + XPF*@Nucleus map + XPG*@Nucleus map → map CDK7:​CyclinH*:​ERCC1:​MNAT1:​RPA2|​pho:​TFIIH1*:​TFIIH2*:​TFIIH3*:​TFIIH4*:​TFIIH5*:​XAB2:​XPA|​S196_pho:​XPB*:​XPD*:​XPF*:​XPG*@Nucleus map
  3. XPA|​S196_pho@Nucleus map + XAB2@Nucleus map → map XAB2:​XPA|​S196_pho@Nucleus map
  4. XPA@Nucleus map → map XPA|​S196_pho@Nucleus map
As Catalyser:
  1. gGG-NER_DNA_st2*@Nucleus map → map gTC-NER_GG-NER_DNA_st3*@Nucleus map
  2. gTC-NER_DNA_st2*@Nucleus map → map gTC-NER_GG-NER_DNA_st3*@Nucleus map
  3. gFanconi_DNA_st5*@Nucleus map → map gTC-NER_GG-NER_DNA_st4*@Nucleus map
  4. gTC-NER_GG-NER_DNA_st3*@Nucleus map → map gTC-NER_GG-NER_DNA_st4*@Nucleus map + Modified 24-32 nucleotides fragment@Nucleus map