Protein HVEM* map

Identifiers
HUGO:TNFRSF14

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Adaptive Immune Response  map  / INHIBITING_CHECKPOINTS  map
 Adaptive Immune Response  map  / ACTIVATING_CHECKPOINTS  map

References
PMID:18097025 PMID:18193050 PMID:20038811 PMID:27192566 PMID:19332782
 DENDRITIC_CELL  map
PMID:18097025
HVEM is expressed in DCs.
PMID:18193050
Binding of HVEM to BTLA or CD160 inhibited T cell activation.

Modifications:
In compartment: Cancer_cell
  1. HVEM*@Cancer_cell map
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. HVEM*@INNATE_IMMUNE_CELL_Cytosol map
In compartment: T_cell
  1. HVEM*@T_cell map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. HVEM*@T_cell map → map HVEM*@T_cell map
    2. Ligands_of_Inhibiting_immune checkpoints@Cancer_cell map → map HVEM*@Cancer_cell map
    3. HVEM*@INNATE_IMMUNE_CELL_Cytosol map → map Immune_checkpoints_T_cells_Inhibitors@INNATE_IMMUNE_CELL_Membrane map
    As Catalyser:
    1. BTLA@T_cell map + PTPN6@T_cell map + PTPN11@T_cell map → map BTLA:​PTPN11:​PTPN6@T_cell map
    2. CD160@T_cell map → map CD160@T_cell map
    3. TRAFs*@T_cell map → map TRAFs*@T_cell map