Antisense RNA MIR141 map

Identifiers
HUGO:MIR141
microRNA 141
HUGO:MIR141, HGNC:31528, ENTREZ:406933, GENECARDS:GC12P007073

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / CAF_INHIBITION_ANTITUMOR  map
 EMT Senescence  map  / EMT_REGULATORS  map

References
PMID:22964023
miR-221-5p is upregulated in CAFS and , miR-141, miR-200b, miR-101-3p are downregulated
TGF-??, IL-6 and RPS6KB1 are predicted as targets for miR-200b/c, IL-6, GRB2 are predicted as targets for miR-141
PMID:20592490
The MIR200 family comprises 5 members (MIR200A, B, C, MIR141 and MIR429).
These 5 members are clustered and expressed as 2 separate polycistronic pri-miRNA transcripts, miR200B-200A-429 and miR200C-141.
These 2 transcripts are located on human chromosomes 1 and 12, respectively.

arMIR141@Nucleus

References
em_emtc_emtc_re1121( EMT Senescence  map ):
PMID:20592490
The MIR200 family comprises 5 members (MIR200A, B, C, MIR141 and MIR429).
These 5 members are clustered and expressed as 2 separate polycistronic pri-miRNA transcripts, miR200B-200A-429 and miR200C-141.
These 2 transcripts are located on human chromosomes 1 and 12, respectively.

Modifications:
In compartment: Cytosol
  1. arMIR141@Cytosol map
In compartment: Nucleus
  1. arMIR141@Nucleus map
Participates in complexes:
In compartment: Cytosol
  1. MIR141:​SMAD2_TGFBR1*@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. arMIR141@Cytosol map → map NEGATIVE_REGULATORS OF_CAF@Cytosol map
  2. arMIR200*@Nucleus map → map arMIR141@Nucleus map
  3. arMIR141@Nucleus map + rSMAD2_TGFBR1*@Nucleus map → map MIR141:​SMAD2_TGFBR1*@Cytosol map
As Catalyser: