Identifiers
FYVE, RhoGEF and PH domain containing 1
"faciogenital dysplasia (Aarskog-Scott syndrome)", FGDY
HUGO:FGD1 HGNC:3663 ENTREZ:2245 UNIPROT:P98174
Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
EMT Senescence / EMT_REGULATORS
EMT Senescence / CYTOSKELETON_POLARITY
References
em_emtc_emtc_re884( EMT Senescence ):
PMID:8836113
GEFs are essential for CDC42 activation. They promote the exchange of GDP to GTP to generate the activated form of CDC42 capable of recognizing downstram targets.
PMID:15743413
PMID:11429692
FGD1,4 are GEFs of CDC42