Complex EIF2S1:EIF2S2:EIF2S3:GDP
Complex composition:
- GDP
- EIF2S2
- EIF2S3
- EIF2S1
EIF2S1|Ser51_pho:EIF2S2:EIF2S3:NDUFA1@Cytosol
Identifiers
NAME:EIF2S1:EIF2S2:EIF2S3:NDUFA1
Maps_Modules
HMC:RESISTING_CELL_DEATH
Regulated Cell Death
/ ER_STRESS
References
PMID:23850759
PMID:16246152
NDUFA4:NDUFB2:NDUFS4:NDUFV3@Cytosol
Identifiers
NAME:NDUFA4:NDUFB2:NDUFS4:NDUFV3
Maps_Modules
HMC:RESISTING_CELL_DEATH
Regulated Cell Death
/ ER_STRESS
References
PMID:23850759
PMID:16246152
Modifications:
Participates in complexes:
In compartment: Cytosol
- NDUFA4:NDUFB2:NDUFS4:NDUFV3@Cytosol
- EIF2S1|Ser51_pho:EIF2S2:EIF2S3:NDUFA1@Cytosol
Participates in reactions:
As Reactant or Product:- EIF2S2@Cytosol
+ EIF2S3:NDUFC1@Cytosol
+ EIF2S1@Cytosol
→
NDUFA4:NDUFB2:NDUFS4:NDUFV3@Cytosol
- EIF2S1|Ser51_pho:EIF2S2:EIF2S3:NDUFA1@Cytosol
→
reduced protein synthesis@Cytosol
- EIF2S1|Ser51_pho:EIF2S2:EIF2S3:NDUFA1@Cytosol
→
reduce translation initiation@Cytosol
- rMet-tRNA*@Cytosol
+ NDUFA4:NDUFB2:NDUFS4:NDUFV3@Cytosol
→
EIF2S1:EIF2S2:EIF2S3:Met-tRNA*@Cytosol
- EIF2S1|Ser51_pho@Cytosol
+ EIF2S2@Cytosol
+ EIF2S3:NDUFC1@Cytosol
→
EIF2S1|Ser51_pho:EIF2S2:EIF2S3:NDUFA1@Cytosol
- EIF2S1|Ser51_pho:EIF2S2:EIF2S3:NDUFA1@Cytosol
+ EIF2B1:EIF2B3:EIF2B4:EIF2B5:NDUFS1@Cytosol
→
EIF2B1:EIF2B2:EIF2S1|Ser51_pho:EIF2S2:NDUFA7:NDUFB4:NDUFB5:NDUFB6@Cytosol
As Catalyser:- gATF4@Nucleus
→
rATF4@Nucleus