Antisense RNA MIR200C map

Identifiers
microRNA 200c
HUGO:MIR200C, HGNC:31580, ENTREZ:406985, GENECARDS:GC12P007072

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map

References
PMID:20592490
The MIR200 family comprises 5 members (MIR200A, B, C, MIR141 and MIR429).
These 5 members are clustered and expressed as 2 separate polycistronic pri-miRNA transcripts, miR200B-200A-429 and miR200C-141.
These 2 transcripts are located on human chromosomes 1 and 12, respectively.

arMIR200C@Nucleus

References
em_emtc_emtc_re1120( EMT Senescence  map ):
PMID:20592490
The MIR200 family comprises 5 members (MIR200A, B, C, MIR141 and MIR429).
These 5 members are clustered and expressed as 2 separate polycistronic pri-miRNA transcripts, miR200B-200A-429 and miR200C-141.
These 2 transcripts are located on human chromosomes 1 and 12, respectively.
em_emtc_emtc_re1144( EMT Senescence  map ):
PMID:21224848
PMID:20706219
BIM1 and TGFB2 are targeted by MIR200C
PMID:22753312
direct regulation of SMAD2 by miR-141/200c/30e
em_emtc_emtc_re1201( EMT Senescence  map ):
PMID:19935649
Targets of miR-200c include stem cell factors, such as Bmi1, Sox2 and KLF4

Modifications:
In compartment: Nucleus
  1. arMIR200C@Nucleus map
Participates in complexes:
In compartment: Cytosol
  1. MIR200C:​SMAD2_TGFB2*@Cytosol map
  2. BIM1_KLF4_SOX2*:​MIR200C@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. arMIR200*@Nucleus map → map arMIR200C@Nucleus map
  2. arMIR200C@Nucleus map + rSMAD2_TGFB2*@Nucleus map → map MIR200C:​SMAD2_TGFB2*@Cytosol map
  3. arMIR200C@Nucleus map + rBIM1_KLF4_SOX2*@Nucleus map → map BIM1_KLF4_SOX2*:​MIR200C@Cytosol map
As Catalyser: