Protein PHLDA3 map

Identifiers
pleckstrin homology-like domain, family A, member 3
HUGO:PHLDA3 HGNC:8934 ENTREZ:23612 UNIPROT:Q9Y5J5

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map
 Regulated Cell Death  map  / CASPASES  map
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / RCD_GENES  map

PHLDA3@Cytosol

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map
 Regulated Cell Death  map  / CASPASES  map
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / RCD_GENES  map

References
rc_re328( Regulated Cell Death  map ):
PMID:19203586
PHLDA3 competes with the PH domain of Akt for binding of membrane lipids, thereby inhibiting Akt translocation to the cellular membrane and activation
PMID:15718470
TORC2 complex as AKT S473 kinase
PMID:22924465
PMID:22475393
ISP1 prevents apoptotic degeneration in primary neurons during oxidant stress through the activation of protein kinase B (Akt1)

Modifications:
In compartment: Cytosol
  1. PHLDA3@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. rPHLDA3@Nucleus map → map PHLDA3@Cytosol map
    As Catalyser:
    1. AKT*@Cytosol map → map AKT*|​S473_pho|​T308_pho@Cytosol map