Reaction state_transition su_mpk1_mpk1_re264 map

p70_alpha_*@Cytoplasm map → p70_alpha_*|​pho@Cytoplasm map

Reaction regulators:
Boolean_logic_gate_and
  1. ERK*|​pho|​pho@Cytoplasm map and PKD1|​unk@Cytoplasm map
Catalysis
  1. ERK*|​pho|​pho@Cytoplasm map
  2. PKD1|​unk@Cytoplasm map


References
PDK1 is a PI3K target leading to activation of P70 (through phosphorylation) and subsequent cell growth.
P70 activation requires both ERK cascade and PI3K/AKT cascade at least in some cell types.
PMID:12040186 PMID:11940578 PMID:10601235 PMID:11431469