Protein SLC2A1 map

Identifiers
solute carrier family 2 member 1
HUGO:SLC2A1 hgnc_id:HGNC:11005 HGNC:11005 ENTREZ:6513 UNIPROT:P11166
solute carrier family 2 (facilitated glucose transporter), member 1
HUGO:SLC2A1 HGNC:11005 ENTREZ:6513 UNIPROT:P11166

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / METABOLIC  map
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / GLUCOSE_METABOLISM  map
 Regulated Cell Death  map  / MITOCHONDRIAL_METABOLISM  map
 RECON2  map

References
PMID:11120745
Glut1 promoter has HIF1 binding site
PMID:25732824
HIF1 upregulates GLUT1 protein level
SLC2A1 (GLUT1) is upregulated in CAFs. It provides enhanced glucose uptake by CAFs.
synonym:GLUT1

SLC2A1@Secretory Granule

Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / GLUCOSE_METABOLISM  map
 Regulated Cell Death  map  / MITOCHONDRIAL_METABOLISM  map

References
rc_re464( Regulated Cell Death  map ):
PMID:15735728
in mouse haemopoietic cell line TonB210, by AKT, upon expression of BCR-ABL or upon IL3

Modifications:
In compartment: Cytosol
  1. SLC2A1@Cytosol map
In compartment: Secretory Granule
  1. SLC2A1@Secretory Granule map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. rSLC2A1@Cytosol map → map SLC2A1@Cytosol map
    2. rSLC2A1@Nucleus map → map SLC2A1@Secretory Granule map
    3. SLC2A1@Secretory Granule map → map SLC2A1@Cytosol map
    As Catalyser:
    1. glucose@default map → map glucose@Cytosol map
    2. glucose@Extracellular space map → map glucose@Cytosol map