Simple molecule piruvat map
piruvat@Cytosol

Identifiers
HUGO:PKM

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / METABOLIC  map

References
PMID:22101652; PMID:19923890
The M1 or M2 splice isoforms of pyruvate kinase (PK), a mandatory regulatory glycolytic enzyme, shift glucose metabolism towards aerobic glycolysis (PKM2) or oxidative phosphorylation (PKM1)
PKM2 and lactate dehydrogenase are highly expressed in the stroma of breast cancer lacking caveolin-1 expression

Modifications:
In compartment: Cytosol
  1. piruvat@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. piruvat@Cytosol map → map lactate@Cytosol map
    2. Phosphoenolpyruvate@Cytosol map → map piruvat@Cytosol map
    3. piruvat@Cytosol map → map TCA_CYCLE@Cytosol map
    As Catalyser: