Protein WIPF1 map

Identifiers
HUGO:WIPF1
WAS/WASL interacting protein family, member 1
HUGO:WIPF1 HGNC:12736 ENTREZ:7456 UNIPROT:O43516

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Adaptive Immune Response  map  / TCR_SIGNALING  map
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map

References
PMID:16606694
PMID:23725295
PMID:22166994
 NATURAL_KILLER  map
CASCADE:KIR2DL1
WIPF1 forms complex with WASP.
WIPF1 (WIP) phosphorylation in NK cells is mediated by PRKCQ (PKC theta)
PMID:17890224
in macrophages WASP and WASP-interacting protein (WIP) form a complex at the phagocytic cup and that the WASP.WIP complex plays a critical role in the phagocytic cup formation.

WIPF1@Cytosol

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map

Modifications:
In compartment: Cytosol
  1. WIPF1@Cytosol map
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. WIPF1@INNATE_IMMUNE_CELL_Cytosol map
In compartment: T_cell
  1. WIPF1@T_cell map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. WASP*|​pho:​WIPF1@INNATE_IMMUNE_CELL_Cytosol map
  2. WASP*|​pho:​WIPF1|​pho@INNATE_IMMUNE_CELL_Cytosol map
  3. ELC_MYOSIN_II*:​MYH9|​hm2:​RLC_MYOSIN_II*|​pho:​WASP*:​WIPF1|​pho@INNATE_IMMUNE_CELL_Cytosol map
In compartment: T_cell
  1. WASP*|​Tyr291_pho:​WIPF1@T_cell map
  2. WASP*|​Tyr291_pho:​WIPF1|​pho@T_cell map
  3. ELC_MYOSIN_II*:​MYH9|​hm2:​RLC_MYOSIN_II*|​pho:​WASP*:​WIPF1|​pho@T_cell map
Participates in reactions:
As Reactant or Product:
  1. WASP*|​Tyr291_pho:​WIPF1@T_cell map → map WASP*|​Tyr291_pho:​WIPF1|​pho@T_cell map
  2. WASP*|​Tyr291_pho|​active@T_cell map + WIPF1@T_cell map → map WASP*|​Tyr291_pho:​WIPF1@T_cell map
  3. ELC_MYOSIN_II*:​MYH9|​hm2:​RLC_MYOSIN_II*|​pho@T_cell map + WASP*|​Tyr291_pho:​WIPF1|​pho@T_cell map → map ELC_MYOSIN_II*:​MYH9|​hm2:​RLC_MYOSIN_II*|​pho:​WASP*:​WIPF1|​pho@T_cell map
  4. ELC_MYOSIN_II*:​MYH9|​hm2:​RLC_MYOSIN_II*|​pho@INNATE_IMMUNE_CELL_Cytosol map + WASP*|​pho:​WIPF1|​pho@INNATE_IMMUNE_CELL_Cytosol map → map ELC_MYOSIN_II*:​MYH9|​hm2:​RLC_MYOSIN_II*|​pho:​WASP*:​WIPF1|​pho@INNATE_IMMUNE_CELL_Cytosol map
  5. WASP*|​pho:​WIPF1@INNATE_IMMUNE_CELL_Cytosol map → map WASP*|​pho:​WIPF1|​pho@INNATE_IMMUNE_CELL_Cytosol map
  6. WASP*|​pho|​active@INNATE_IMMUNE_CELL_Cytosol map + WIPF1@INNATE_IMMUNE_CELL_Cytosol map → map WASP*|​pho:​WIPF1@INNATE_IMMUNE_CELL_Cytosol map
  7. WIPF1@Cytosol map + WIPF2@Cytosol map → map WIP*@Cytosol map
As Catalyser:
  1. Actin cytoskeletal*@T_cell map → map Actin cytoskeletal*|​hm2@T_cell map
  2. Actin cytoskeletal*@INNATE_IMMUNE_CELL_Cytosol map → map Actin cytoskeletal*|​hm2|​active@INNATE_IMMUNE_CELL_Cytosol map