Reaction heterodimer_association rc_re1645
CUL3:RBX1@Cytosol
+ Caspase8,10*:DR4/5*|gly|pal@Cytosol
→ CUL3:Caspase8,10*|ubi:DR4/5*|gly|pal:RBX1@Cytosol
No reaction regulators
References
PMID:19427028
Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling