Reaction state_transition rc_re1044 map

DNA~integrity@Nucleus map → DNA~fragmentation@Nucleus map

Reaction regulators:
Boolean_logic_gate_and
  1. DFFB@Nucleus map and H2AFX|​pho|​Y142_pho@Nucleus map
Catalysis
  1. PPIA:​cleaved~AIFM1*@Nucleus map
  2. DFFB@Nucleus map
  3. ENDOG@Nucleus map
  4. H2AFX|​pho|​Y142_pho@Nucleus map


References
PMID:12198487
by AIFM1
PMID:14716299
in vitro, by AIF+CypA
PMID:11452314
in DFFB KO MEFs by ENDOG
PMID:16818236