Reaction heterodimer_association rc_re486 map

APAF1@Cytosol map + HSP70*@Cytosol map → rc_s1590

No reaction regulators

References
PMID:10934467
in 293, HeLa and Jurkat cells, interaction HSP70 - APAF1
in vitro, the interaction is ATP dependent
HSP70 interactions competes for oligomerization and formation of the apoptosome
PMID:10934466
in vitro, HSP70 blocks the recruitment of CASP9 into the apoptosome by binding to APAF1