Reaction translation rc_re44 map

rMCL1@Nucleus map → MCL1@Mitochondrial inner membrane map

Reaction regulators:
Boolean_logic_gate_or
  1. arMIR29*@Cytosol map and and arMIR153*@Cytosol map and arMIR133B@Cytosol map
Catalysis
  1. Capped RNA translation@Cytosol map
Inhibition
  1. arMIR101*@Cytosol map
  2. arMIR133B@Cytosol map
  3. arMIR153*@Cytosol map
  4. arMIR29*@Cytosol map


References
PMID:17404574
in human immortalized non malignant H69 cholangiocyte and malignant KMCH cholangiocarcinoma cell lines, MIR29B1 targets MCL1
PMID:19155302
MCL1 is a target of MIR101
PMID:19676043
in DBTRG-05MG human glioblastoma cell line, MCL1 targeted by MIR153
PMID:19654003
in H2009 human lung adenocarcinoma cells, MCL1 is a target of MIR133B
PMID:19966861
in Jurkat, HeLa, U937, glycolysis inhibition by 2deoxy glucose causes a specific block in transltion of MCL1, through a AMPK - TOR pathway