Reaction heterodimer_association ce_re121
CTIP*|emp|S372_pho|T847_pho|S267_pho|BRCA1-dep_ubi@Nucleus
+ BRCA1|S988_pho|S1387_pho|S1423_pho|S1497_pho|S1524_pho|active@Nucleus
→ BRCA1|S988_pho|S1387_pho|S1423_pho|S1497_pho|S1524_pho:CTIP*|emp|S372_pho|T847_pho|S267_pho|BRCA1-dep_ubi@Nucleus
No reaction regulators
References
The shift from C_NHEJ to HR is regulated by the CtIP and BRCA1. CDK1-dependent phosphorylation of CtIP regulates the shift: PMID:19357644
PMID:15485915