Reaction translation re386 map

rIL23A@Cytosol map → IL23A@Cytosol map

Reaction regulators:
Catalysis
  1. CSF2:​CSF2RA:​CSF2RB:​JAK2@Membrane map





Identifiers

Maps_Modules

References
PMID:17404308
CSF1 downregulates TNF, IL-23p19, IL-12p40 expression probably via induction of acomulation of p50 homodimer and inhibition of p65/p50 NF-kB signaling.
CSF2 upregulates expression of TNF, and have positive influence on IL12p70 (p40+p35), IL23 (p40+p19) expression, probably via induction rapid IkBa degradetion, RELA nuclear translocation and formation p65/p50 heterodimers provided induction of NFkB signaling.