Protein CD18* map

Identifiers
HUGO:ITGB2

Maps_Modules
MODULE:MACROPHAGE
MODULE:IMMUNOSTIMULATORY_CYTOKINE_EXPRESSION

References
PMID:12413632
CD18/CD11-ICAM-1 adhesion between effector and target cells plays an
important role in macrophage-mediated tumor cytotoxicity.
PMID:1679046
INFG apregulates CD18 surface expression.
Inhibition of CD18 inhibits monocyte binding to tumor target cells and tumoricidal activity.

CD18*@Cytosol

Identifiers

Maps_Modules

References

Modifications:
In compartment: Cytosol
  1. CD18*@Cytosol map
Participates in complexes:
In compartment: Membrane
  1. CD11*:​CD18*@Membrane map
Participates in reactions:
As Reactant or Product:
  1. rCD18@Cytosol map → map CD18*@Cytosol map
  2. CD11*:​CD18*@Membrane map → map Migration into tumor@default map
  3. CD18*@Cytosol map + CD11*@Cytosol map → map CD11*:​CD18*@Membrane map
  4. CD11*:​CD18*@Membrane map → map Macrophage adhesion to tumor cell@Membrane map
As Catalyser: