Protein TXN
MODULE:MACROPHAGE
HUGO:TXN
MODULE:NO_ROS_PRODUCTION
PMID:20414655, PMID:18792398
Trx is one of the main intracellular oxido-reductases
TXN expression is upregulated in activated macrophages,
DC and probably macrophages secrete thioredoxin which reduces extracellular cystine to cysteine, which is then available for the uptake by T cells through their ASC transporter

---

Modifications:
In compartment: Cytosol

1. TXN@Cytosol

In compartment: default

1. TXN@default

Participates in complexes:

Participates in reactions:
As Reactant or Product:

1. TXN@Cytosol → TXN@default

As Catalyser:

1. Cystine@default → Cysteine@default
2. Cystine@Cytosol → Cysteine@Cytosol