Protein VEGFA map

Identifiers
HUGO:VEGFA

Maps_Modules
MODULE:MACROPHAGE
MODULE:MDSC
MODULE:IMMUNOSUPPRESSIVE_CYTOKINE_PATHWAYS

References
HMGB1 markedly increased the expression of the genes for VEGF, and TGFB1 in
peritoneal macrophages.
PMID:23390297, PMID:22461508
MIF signaling induces angiogenesis provavly via upregulation of MMP9, VEGF expression.
PMID:22067385
c-MYC is expressed in tumor-associated macrophages, and its inhibition blocks the expression of protumoral genes including VEGF, MMP9, HIF-1A, and TGFB.
PMID:20644162
Cytokine-induced CD33+ human MDSCs have upregulated iNOS, TGF??, VEGF.
PMID:18776941
Myeloid-derived suppressor cells and macrophages isolated from mouse tumors displayed activated Stat3 and induced angiogenesis in an in vitro tube formation assay via Stat3 induction of angiogenic factors, including VEGF and bFGF.

VEGFA@Cytosol

Identifiers

Maps_Modules

References

VEGFA@default

Identifiers

Maps_Modules

References

Modifications:
In compartment: Cytosol
  1. VEGFA@Cytosol map
In compartment: default
  1. VEGFA@default map
Participates in complexes:
In compartment: default
  1. VEGFA:​trVEGFR1*@default map
Participates in reactions:
As Reactant or Product:
  1. rVEGFA@Cytosol map → map VEGFA@Cytosol map
  2. VEGFA@Cytosol map → map VEGFA@default map
  3. VEGFA@default map → map Angiogenesis@default map
  4. VEGFA:​trVEGFR1*@default map → map degraded
  5. trVEGFR1*@default map + VEGFA@default map → map VEGFA:​trVEGFR1*@default map
  6. VEGFA:​trVEGFR1*@default map → map Angiogenesis@default map
As Catalyser: