Protein HSP70* map
MODULE:MDSC
HUGO:HSPA1A HGNC:5232 ENTREZ:3303 UNIPROT:P08107 GENECARDS:HSPA1A REACTOME:56682 KEGG:3303 ATLASONC:GC_HSPA1A WIKI:HSPA1A HUGO:HSPA1B HGNC:5233 ENTREZ:3304 UNIPROT:P08107 GENECARDS:HSPA1B REACTOME:56682 KEGG:3304 ATLASONC:GC_HSPA1B WIKI:HSPA1B
heat shock 70kDa protein 1B
HUGO:HSPA1B HGNC:5233 ENTREZ:3304 UNIPROT:P08107 GENECARDS:HSPA1B REACTOME:56682 KEGG:3304 ATLASONC:GC_HSPA1B WIKI:HSPA1B HUGO:HSPA1A HGNC:5232 ENTREZ:3303 UNIPROT:P08107 GENECARDS:HSPA1A REACTOME:56682 KEGG:3303 ATLASONC:GC_HSPA1A WIKI:HSPA1A
heat shock 70kDa protein 1-like
HUGO:HSPA1L HGNC:5234 ENTREZ:3305 UNIPROT:P34931 GENECARDS:HSPA1L KEGG:3305 ATLASONC:GC_HSPA1L WIKI:HSPA1L
"heat shock 70kD protein 1A", HSPA1
MODULE:IMMUNOSTIMULATORY_CYTOKINE_PATHWAYS
PMID:20093776
Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells via TLR2/MyD88 dependent IL6 expression.
Modifications:
In compartment: default
  1. HSP70*@default map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
      As Catalyser:
      1. TLR2/4*@Membrane map + LY96@Membrane map + TIRAP@Membrane map + MYD88@Membrane map + CD14@Membrane map → map CD14:​LY96:​MYD88:​TIRAP:​TLR2/4*@Membrane map