Gene IRAK3 map

Identifiers
HUGO:IRAK3

Maps_Modules
MODULE:MACROPHAGE
MODULE:IMMUNOSTIMULATORY_CYTOKINE_PATHWAYS

References
PMID:12150927
IRAK3 (IRAK-M) is a negative regulator of Toll-like receptor signaling
in macrophages. It prevented dissociation of IRAK and IRAK-4 from MyD88 and formation of IRAK-TRAF6 complexes.
PMID:21278795
TGFB-induced IRAK3 (IRAK-M) expression in tumor-associated macrophages
and inhibit TLR-dependent signaling

gIRAK3@Cytosol

Identifiers

Maps_Modules

References

Modifications:
In compartment: Cytosol
  1. gIRAK3@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gIRAK3@Cytosol map → map rIRAK3@Cytosol map
    As Catalyser: