Protein CD40LG map

Identifiers
HUGO:CD40LG

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Adaptive Immune Response  map  / ACTIVATING_CHECKPOINTS  map

References
PMID:11581322 PMID:8760829 ??17200410 PMID:23125331 PMID:15034038 PMID:17371980
 DENDRITIC_CELL  map
PMID:11581322
CD40LG induce maturation of DC.
PMID:8760829
Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation.
PMID:??17200410, PMID:23125331, PMID:15034038
pDCs stimulated with IL-3 plus CD40L induce production ICOS-L and expression of OX40L..

Modifications:
In compartment: T_cell
  1. CD40LG@T_cell map
Participates in complexes:
In compartment: Cancer_cell
  1. CD40:​CD40LG@Cancer_cell map
Participates in reactions:
As Reactant or Product:
  1. rCD40LG@T_cell map → map CD40LG@T_cell map
  2. Ligands_of_activating_immune checkpoints@Cancer_cell map → map CD40LG@T_cell map
  3. CD40LG@T_cell map + CD40@Cancer_cell map → map CD40:​CD40LG@Cancer_cell map
As Catalyser: