Complex BCL10:CARD11:MALT1 map
Complex composition:

  1. CARD11 map
  2. MALT1 map
  3. BCL10 map

BCL10:​CARD11|​pho:​MALT1|​ubi@T_cell

Identifiers
NAME:BCL10:CARD11:MALT1

References
PMID:24560716
ad_re400( Adaptive Immune Response  map ):
PMID:14660645, PMID:18264787, PMID:11460167
Activated TAK1 phosphorylates IKK-beta proteins
leading to activation of NF-??B downstream of HMGB1.
PMID:21232017, PMID:21133840, PMID:17301840
PMID:24958845, PMID:24699077
The LUBAC complex ubiquitinates NEMO, a subunit of the IKK complex downstream of TNF and upregulates IkBa degradetion.
PMID:11280761
VEGF signaling blocs TNF-?? induced activation of I??B kinase (IKK complex).This decreased IKK activation correlated with the inhibition of I??B?? phosphorylation and degradation of I??B?? and I??B?? in HPCs, and this inhibition is inhdependent or FLT1 and KDR

BCL10:​CARD11|​pho:​MALT1@T_cell

Identifiers
NAME:BCL10:CARD11:MALT1

References
PMID:24560716

Modifications:
Participates in complexes:
In compartment: T_cell
  1. BCL10:​CARD11|​pho:​MALT1@T_cell map
  2. BCL10:​CARD11|​pho:​MALT1|​ubi@T_cell map
Participates in reactions:
As Reactant or Product:
  1. MALT1@T_cell map + BCL10@T_cell map + CARD11|​pho|​active@T_cell map → map BCL10:​CARD11|​pho:​MALT1@T_cell map
  2. BCL10:​CARD11|​pho:​MALT1@T_cell map → map BCL10*@T_cell map + MALT1@T_cell map + CARD11|​pho|​active@T_cell map
  3. BCL10:​CARD11|​pho:​MALT1@T_cell map → map BCL10:​CARD11|​pho:​MALT1|​ubi@T_cell map
As Catalyser:
  1. IKBKG:​IKK_alpha_*:​IKK_beta_*@T_cell map → map IKBKG|​ubi:​IKK_alpha_*:​IKK_beta_*|​pho@T_cell map