Protein CD70 map

Identifiers
HUGO:CD70

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Adaptive Immune Response  map  / ACTIVATING_CHECKPOINTS  map

References
PMID:19062317 PMID:17237405
 DENDRITIC_CELL  map
CD70 is a costimulatory ligand acquired upon DC maturation. It stimulates T-cells and provides tumor regression.
PMID:17237405
Surface expression of CD70 in DC is TLR and CD40 dependent.

Modifications:
In compartment: Cancer_cell
  1. CD70@Cancer_cell map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. Ligands_of_activating_immune checkpoints@Cancer_cell map → map CD70@Cancer_cell map
    As Catalyser:
    1. CD27@T_cell map → map CD27@T_cell map