Protein GSK3* map

Identifiers
HUGO:GSK3B HUGO:GSK3A
HUGO:GSK3A
HUGO:GSK3B
glycogen synthase kinase 3 alpha
HUGO:GSK3A HGNC:4616 ENTREZ:2931 UNIPROT:P49840 GENECARDS:GSK3A REACTOME:69666 ATLASONC:GC_GSK3A WIKI:GSK3A
glycogen synthase kinase 3 beta
HUGO:GSK3B HGNC:4617 ENTREZ:2932 UNIPROT:P49841 GENECARDS:GSK3B REACTOME:404223 ATLASONC:GSK3BID40761ch3q13 WIKI:GSK3B

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Adaptive Immune Response  map  / TCR_SIGNALING  map
 Innate Immunity  map  / IMMUNOSTIMULATORY_CORE_PATHWAYS  map
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / WNT_CANONICAL  map
 Survival  map  / WNT_NON_CANONICAL  map

References
PMID:19836308 PMID:26885856 PMID:23732914
PMID:16713974
AKT kinases phosphorylate GSK3 proteins and inhibit its activity downstream of TLR signaling.
IFNG prevents this inactivation.
PMID:19366350

Modifications:
In compartment: T_cell
  1. GSK3*@T_cell map
  2. GSK3*|​pho@T_cell map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. GSK3*@T_cell map → map GSK3*|​pho@T_cell map
    As Catalyser:
    1. NFAT*@T_cell map → map NFAT*|​pho@T_cell map
    2. DPYSL2@T_cell map → map DPYSL2|​Thr509/514_pho@T_cell map
    3. rTBX21@T_cell map → map TBX21@T_cell map