→ E-Cadherin*@Lysosome References
PMID:11294891
PMID:22674073
Rac1 Regulates Adherens Junctions through Endocytosis of E-Cadherin.
Rac1 has an ambivalent role on adherens junction. It favourise them in some case because it favours E-cadherin endocytose, however it does promote an endocytose towards degradation rather than recycling.
Rac1 thus favours the lowering of AJ, even if it does not favourise their complete depletion. The adjustment variable being the amout of Trans-activated E-cahderin