Reaction known_transition_omitted em_emtc_emtc_re991 map

Actinin*@Cytosol map → Actinin*|​pho@Cytosol map

Reaction regulators:
Catalysis
  1. FAK1*|​Y_pho|​pho|​active@Cytosol map


References
PMID:15688067
Alpha-actinin is a cytoskeletal protein that binds to viculin (VCL).
Via this binding, Alpha-actinin crosslinks actin (in actomyosin stress fibres) and tether them to the focal contacts.
Phosphorylation of alpha-actinin by FAK1 (PTK2) reduces the crossliking of stress fibres and prevents the maturation of focal contacts.