References
The most known RhoB_GDIs are ARHGDIA and ARHGDIG.
They bind to RhoB and suppress its activation.
PMID:11368848
PMID:8939998
RhoGDI-3 (ARHGDIG) interacts specifically with GDP- and GTP-bound forms of post-translationally processed RhoB and RhoG proteins.
No interaction is found with RhoA, RhoC, or Rac1 proteins.
RhoGDI-3 is able to inhibit GDP/GTP exchange of RhoB and to release GDP-bound but not GTP-bound RhoB from cell membranes.