References
PMID:19418635
GJD2 is widely expressed in neurons and was previously shown to interact with the PDZ domain-containing protein ZO-1.
Direct association of connexin36 (GJD2) with ZO-2 and ZO-3 was also demonstrated.
PMID:15558297
Association of connexin36 with ZO-1 in HeLa cells, betaTC-3 cells, pancreas, and adrenal gland.
The functional significance of Cx36/ZO-1 interaction remains to be established
Interestingly, ZO-1 was not associated with Cx36 intracellularly, suggesting that functions of its interaction with at least Cx36 may be restricted to intact gap junctions at plasma membranes.
PMID:16650609
Association of connexin36 and ZO-1 with ZO-2 and the transcription factor ZO-1-associated nucleic acid-binding protein at neuronal gap junctions in rodent retina.
PMID:17681699
In the outer plexiform layer of mouse retina, ZO-1 interacts with connexin36 but not with Cx57, and there is an absence of connexin57/connexin36 heterotypic gap junctional coupling in mouse retina