→ rTGFB3@Nucleus References
PMID:11790723
Whereas TGF-b1 and 2 are proscarring growth factors, TGF-b3 is antiscarring
TGF-b1, 2, and 3 are embryonically expressed in skin and up-regulated at adult wound sites
Overlapping expression patterns of HIF-1a and TGF-b3 in vivo
TGF-b1 mRNA expression was serum- but not hypoxia-inducible.
In contrast, TGF-b3 mRNA expression was hypoxia-inducible, but not serum- inducible
Basal TGF-b3 levels were nearly undetectable in HIF-1a ???/??? MEFs, demonstrating that TGF-b3 might be a HIF-1a target gene
PMID:9278421
PMID:10712429
HIF1 target genes include TGFB3
PMID:16887934
VEGF, EG-VEGF, TGFB3 are target genes of HIF1