Protein ITGA2 map

Identifiers
integrin subunit alpha 2
HUGO:ITGA2 hgnc_id:HGNC:6137 HGNC:6137 ENTREZ:3673 UNIPROT:P17301
HUGO:ITGA2
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
CD49B
HUGO:ITGA2 HGNC:6137 ENTREZ:3673 UNIPROT:P17301

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / CELL_MATRIX_ADHESIONS  map
 EMT Senescence  map  / ECM  map

References
CASCADE:INTEGRIN
PMID:9456329;PMID:11112697
Integrin ??2??1 is a heterodimeric adhesive protein receptor belonging to the ??1 subfamily. It serves as a collagen receptor on fibroblasts and platelets and additionally as a laminin receptor on epithelial and endothelial cells
Collagen signaling nduces NF-??B Activity in fibroblasts probably via this receptor

Modifications:
In compartment: Cytosol
  1. ITGA2@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. ITGB1@Cytosol map + ITGA2@Cytosol map → map ca_s4672
    2. rITGA2@Nucleus map → map ITGA2@Cytosol map
    3. ITGA2@Cytosol map + ITGB1@Cytosol map → map em_emtc_emtc_s3071
    4. rITGA2@Nucleus map → map ITGA2@Cytosol map
    5. ITGB1@Cytosol map + ITGA2@Cytosol map → map mo_s2
    As Catalyser: