Protein DPP4 map

Identifiers
HUGO:DPP4

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / MATRIX_REGULATION  map

References
PMID:1345821; PMID:10569731??
DPP4 is expressed in breast?? fibroblasts
PMID:17981655
CD26/DPPIV can associate with several proteins, among them fibroblast activating protein-alpha (FAP-alpha), plasminogen, adenosine deaminase (ADA), the tyrosine phosphatase CD45, and the chemokine receptor CXCR4. It can also bind to the extracellular matrix (ECM) and depending on the presence of other ligands, this process can either lead to increased or decreased invasive activity of the cells on which it is expressed. As a result of these characteristics, CD26/DPPIV plays an important??role??in tumor biology, and is useful as a marker for various cancers

Modifications:
In compartment: Cytosol
  1. DPP4@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. DPP4@Cytosol map → map ECM_REGULATION@default map
    As Catalyser: