Protein NDUFA4L2 map

Identifiers
HUGO:NDUFA4L2

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / METABOLIC  map

References
CASCADE:TGFB
PMID:25732824
NDUFA4L2 (NADH dehydrogenase [ubiquinone] 1 alpha subcomplex, 4-like 2), a negative regulator of mitochondrial complex 1, was upregulated in CAFs
The accumulation of HIF-1??, in turn, promotes glycolysis by increasing the uptake of glucose, upregulating expression of glycolytic enzymes under normoxic conditions, and inhibiting oxidative phosphorylation by upregulating NDUFA4L2 downstream of TGFB.

Modifications:
In compartment: Cytosol
  1. NDUFA4L2 @Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. rNDUFA4L2@Cytosol map → map NDUFA4L2 @Cytosol map
    2. NDUFA4L2 @Cytosol map → map TCA_CYCLE@Cytosol map
    3. NDUFA4L2 @Cytosol map → map Glycolysis@Cytosol map
    As Catalyser: