Identifiers
Ultraviolet light or radiation (UV-A and UV-B)
Damage types are bulky adducts, 6-4 phosphoproducts, cyclobutane pyrimidinr dimer (CPD), pyrimidine dimer, thymidine dimer.
Causes direct damage, NER gap, stalled transcription and stalled replication fork or indirect damage by formation of free radicals
Maps_Modules
HMC:GENOME_INSTABILITY_AND_MUTATION
Cell Cycle DNA Repair / HR
Cell Cycle DNA Repair / C_NHEJ
Cell Cycle DNA Repair / FANCONI
Cell Cycle DNA Repair / TLS
Cell Cycle DNA Repair / DR
References
http://dnatraffic.ibb.waw.pl/classification/dna_damages
PMID:22258607, PMID:19267553, PMID:18256616
For NER
PMID:22743272, PMID:22822215, PMID:22492724, PMID:22373527
For C_NHEJ
PMID:17293412, PMID:15367581
FOR HR
PMID:21646340, PMID:22987150, PMID:22860035
For TLS
PMID:22521143
For Fanconi
PMID:17145857
ce_re513( Cell Cycle DNA Repair ):
For C_NHEJ activation by IR
PMID:20691907, PMID:23012265, PMID:21785230
For C_NHEJ activation by UV
Topoisomerate inhibitors bloch double strand DNA repair by HR, C_NHEJ and Fanconi pathways
PMID:23259582
PMID:22123462, PMID:20693240
PMID:21414716, PMID:23157317
For activation by Dbait
PMID:22068457, PMID:22815765, PMID:22042585, PMID:19621083
ce_re515( Cell Cycle DNA Repair ):
FOR HR activation by IR
PMID:20723763
For HR activation by UV
PMID:21885354, PMID:22987150, PMID:20206282, PMID:19398948, PMID:1575062
Interstrand crosslinking agents activate HR
PMID:21701511
ce_re516( Cell Cycle DNA Repair ):
For actovation of TLS by UV
For actIvation of TLS by interstrand crosslinking agents
PMID:20015866, PMID:15155842, PMID:22122464, PMID:23106263, PMID:21666254, PMID:20658647
ce_re517( Cell Cycle DNA Repair ):
UV light causes bulky adducts damage in DNA that repared by NER pathway
For activation of NER by UV
Interstrand crosslinking agents induce NER
ROS activate NER for repating intrastrand crosslink
PMID:22581771
ROS activate NER for bulky adducts
PMID:18189366
ce_re518( Cell Cycle DNA Repair ):
Damage caused by UV light pyrimidine dimers is repaired by DR
ce_re519( Cell Cycle DNA Repair ):
PMID:22743272, PMID:22822215, PMID:22492724, NER:22373527
Transcription-dependent NER and damage by UV
PMID:20045328, PMID:14599741
ce_re520( Cell Cycle DNA Repair ):
Fanconi is activated by interstrand crosslinking agents
PMID:23444773, PMID:21948210, PMID:21701511