Gene GPT2 map

Identifiers
HUGO:GPT2

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / METABOLIC  map

References
CASCADE:TGFB
CASCADE:PDGF
PMID:25732824
the expression of ALT2 (GPT2) was significantly increased in induced CAFs (Figure 4C), suggesting that the slight elevation of ??-KG is likely through the glutamate pathway by feedback upregulation of ALT2 in CAFs and fibroblasts with IDH3?? knockdown.
ALT2 is upregulated downstream of TGFB and PDGF.

Modifications:
In compartment: Cytosol
  1. gGPT2@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gGPT2@Cytosol map → map rGPT2@Cytosol map
    As Catalyser: