Gene SLC2A1 map

Identifiers
HUGO:SLC2A1
solute carrier family 2 (facilitated glucose transporter), member 1
HUGO:SLC2A1 HGNC:11005 ENTREZ:6513 UNIPROT:P11166

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / METABOLIC  map
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / GLUCOSE_METABOLISM  map
 Regulated Cell Death  map  / MITOCHONDRIAL_METABOLISM  map

References
PMID:11120745
Glut1 promoter has HIF1 binding site
PMID:25732824
HIF1 upregulates GLUT1 protein level
SLC2A1 (GLUT1) is upregulated in CAFs. It provides enhanced glucose uptake by CAFs.
synonym:GLUT1

gSLC2A1@Nucleus

Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / GLUCOSE_METABOLISM  map
 Regulated Cell Death  map  / MITOCHONDRIAL_METABOLISM  map

References
rc_re174( Regulated Cell Death  map ):
PMID:7493931
in HepG2 by HIF1 (EMSA, reporter plasmids)
PMID:9525945
in chinese hamster ovary cells by HIF1
PMID:15059920
in Saos2, in human embryonal rhabdomyosarcoma derived RD (ATCC no. CCL-136), in murine skeletal muscle-derived C2C12 myoblasts (ATCC no. CRL-1772), by TP53 (luciferase reporter)

Modifications:
In compartment: Cytosol
  1. gSLC2A1@Cytosol map
In compartment: Nucleus
  1. gSLC2A1@Nucleus map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gSLC2A1@Cytosol map → map rSLC2A1@Cytosol map
    2. gSLC2A1@Nucleus map → map rSLC2A1@Nucleus map
    As Catalyser: