Identifiers
HUGO:CCL20
Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
Cancer Associated Fibroblasts / CYTOKINES_CHEMOKINES_PRODUCTION
References
CASCADE:IL1
PMID:21847358
IL-1?? was established as the initiator of the enhanced production of inflammatory factors through the binding of IL-1?? to IL-1 receptor 1 (IL-1R1) expressed predominantly by CAFs.
IL1A upregulates expression of IL6, CCL20, CXCL8, COX2 in CAFs.
IL-1?? Expression Levels in prostate cancer Tissue Correlated to Poor Clinical Outcome