RNA ITGA5 map

Identifiers
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
HUGO:ITGA5, HGNC:6141, ENTREZ:3678, GENECARDS:GC12M054789

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / CELL_MATRIX_ADHESIONS  map

References
PMID:19161977
In the endoplasmic reticulum, integrin subunits find their binding partners and form heterodimers.
Monomeric integrins never reach the cell surface.
PMID:19487819
During gastrulation, type 1 EMT is associated with de novo expression of a5b1, which is a receptor for fibronectin.
Type 2 EMT in experimental kidney fibrosis is associated with increased a5 integrin expression.

Modifications:
In compartment: Nucleus
  1. rITGA5@Nucleus map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gITGA5@Nucleus map → map rITGA5@Nucleus map
    2. rITGA5@Nucleus map → map ITGA5@Cytosol map
    As Catalyser: