Identifiers
glycogen synthase kinase 3 beta
HUGO:GSK3B, HGNC:4617, ENTREZ:2932, GENECARDS:GC03M119540??
Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
EMT Senescence / EMT_REGULATORS
References
PMID:15465828
GSK-3b plays a critical role in cell survival by phosphorylating nuclear factor-??B (NF-??B) p65 subunit, leading to NF-??B transactivation in hepatocytes
This phosphorylation negatively regulates basal p65 NF-kappaB activity.