Protein G0S2 map

Identifiers
G0/G1switch 2
HUGO:G0S2 HGNC:30229 ENTREZ:50486 UNIPROT:P27469

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / CASPASES  map
 Regulated Cell Death  map  / MOMP_REGULATION  map

G0S2@Cytosol

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / CASPASES  map
 Regulated Cell Death  map  / MOMP_REGULATION  map

References
rc_re1001( Regulated Cell Death  map ):
PMID:19706769
in HEK293, co-precipitation of ectopically expressed tagged proteins
in HeLa cells infected with G0S2-HA Ad virus, co-precipitation of endogenous BCL2 with HA antibody
in HCT116 (transient transfection), interaction detected by FRET
Competition between G0S2 and BAX for binding to BCL2
in HEK293, co-IP experiments with tagged protein shows that G0S2 competes with BAX for binding to BCL2

Modifications:
In compartment: Cytosol
  1. G0S2@Cytosol map
Participates in complexes:
In compartment: Mitochondrial inner membrane
  1. BCL2:​G0S2@Mitochondrial inner membrane map
Participates in reactions:
As Reactant or Product:
  1. BCL2|​unk@Mitochondrial inner membrane map + G0S2@Cytosol map → map BCL2:​G0S2@Mitochondrial inner membrane map
  2. rG0S2@Nucleus map → map G0S2@Cytosol map
As Catalyser: