Protein PML map

Identifiers
promyelocytic leukemia
HUGO:PML HGNC:9113 ENTREZ:5371 UNIPROT:P29590
PML
HUGO:PML HGNC:9113 ENTREZ:5371 UNIPROT:P29590 GENECARDS:PML REACTOME:61894 KEGG:5371 ATLASONC:PMLID41 WIKI:PML

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / RCD_GENES  map
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / PI3K_AKT_MTOR  map
 Survival  map  / WNT_NON_CANONICAL  map

References
PMID:20452955

PML@PML Body

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / RCD_GENES  map

References
rc_re888( Regulated Cell Death  map ):
PMID:16915281
in mouse, PML directs mTOR to the nucleus, thereby inhibiting its interaction with Rheb and its ability to promote HIF1A translation

Modifications:
In compartment: PML Body
  1. PML@PML Body map
Participates in complexes:
In compartment: Nucleus
  1. PML:​PML|​unk|​unk@Nucleus map
  2. PML:​PML|​unk|​unk@Nucleus map
  3. NFAT2*|​K702_unk|​K914_unk:​PML:​PML|​unk|​unk@Nucleus map
  4. NFAT2*|​K702_unk|​K914_unk:​PML:​PML|​unk|​unk@Nucleus map
  5. PML:​PP2A_A*:​PP2A_B*:​PP2A_C*@Nucleus map
Participates in reactions:
As Reactant or Product:
  1. PP2A_A*:​PP2A_B*:​PP2A_C*@Nucleus map + su_akt1_s_akt2_s444 → map PML:​PP2A_A*:​PP2A_B*:​PP2A_C*@Nucleus map
  2. NFAT2*|​K702_unk|​K914_unk@Nucleus map + PML:​PML|​unk|​unk@Nucleus map → map NFAT2*|​K702_unk|​K914_unk:​PML:​PML|​unk|​unk@Nucleus map
As Catalyser:
  1. MLST8:​MTOR:​RPTOR|​unk@Nucleus map → map MLST8:​MTOR:​RPTOR|​unk@PML Body map
  2. AKT*|​pho|​T450_pho|​pho|​active@Nucleus map → map AKT*|​emp|​T450_pho|​pho@Nucleus map
  3. gIL2@Nucleus map → map rIL2@Nucleus map