Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
EMT Senescence / EMT_REGULATORS
References
PMID:16556862
ROS regulate MMP gene expression and activation of proenzymes. MMP-1, MMP-2, MMP-7, and MMP-9 are activated by ROS through interactions with thiol groups
References
em_re1529( EMT Senescence ):
PMID:22439866
c-Myb regulates matrix metalloproteinases 1/9, and cathepsin D, there is implications for matrix-dependent breast cancer cell invasion and metastasis.