Protein KCNIP3 map

Identifiers
Kv channel interacting protein 3, calsenilin
HUGO:KCNIP3 HGNC:15523 ENTREZ:30818 UNIPROT:Q9Y2W7

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / CASPASES  map
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / RCD_GENES  map

References
synonym:DREAM

KCNIP3@Nucleus

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / CASPASES  map
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / RCD_GENES  map

References
rc_re615( Regulated Cell Death  map ):
hierarchical:post-MOMP
reactionType:casp.cleavage
PMID:12217801
in Jurkat, Fas induces HRK expression and DREAM:HRK-promoter dissociation (EMSA), which is blocked by z-VAD-fmk
in vitro, caspase 3 could cleave DREAM
rc_re647( Regulated Cell Death  map ):
PMID:11331593
in in FDCP-Mix and FL5.12 hematopoietic progenitor cells, by DREAM/KCNIP3 inhibition released upon IL3 withdrawal
in Jurkat, upon Fas

Modifications:
In compartment: Nucleus
  1. KCNIP3@Nucleus map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. KCNIP3@Nucleus map → map cleaved~KCNIP3*@Nucleus map
    As Catalyser:
    1. gHRK@Nucleus map → map rHRK@Nucleus map