Protein ICOSLG
Identifiers
HUGO:ICOSLG
Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
Adaptive Immune Response
/ ACTIVATING_CHECKPOINTS
References
PMID:11007762 PMID:20116985
DENDRITIC_CELL
PMID:11007762
ICOSLG (B7RP1) is expressed on PB B cells and monocytes, and on PB monocyte-derived DC.
It is the ligand to the co-stimulatory protein ICOS of T cells.
Modifications:
In compartment: Cancer_cell
- ICOSLG@Cancer_cell
In compartment: INNATE_IMMUNE_CELL_Membrane
- ICOSLG@INNATE_IMMUNE_CELL_Membrane
Participates in complexes:
Participates in reactions:
As Reactant or Product:- Ligands_of_activating_immune checkpoints@Cancer_cell
→
ICOSLG@Cancer_cell
- ICOSLG@INNATE_IMMUNE_CELL_Membrane
→
Immune_checkpoints_T_cells_Activators@default
As Catalyser:- ICOS@T_cell
→
ICOS@T_cell