Complex BAD:BCL2 map
Complex composition:

  1. BAD map
  2. BCL2 map

BAD|​S91_unk:​BCL2@Mitochondrial inner membrane

Identifiers
NAME:BAD:BCL2

References
rc_re597:( Regulated Cell Death  map ) testtest
rc_re1420( Regulated Cell Death  map ):
PMID:8929532
in vitro RAF1:BCL2 interaction
in 293, overexpression of BCL2 induces relocalization of RAF1-GFP to mitochondria
in vitro phosphorylation of BAD by RAF1
in 293T, over-expression of a mitochondria-targeted version of RAF1 induces phosphorylation of BAD (controls: plasma membrane targeted RAF1, kinase dead mutant)
BCL2 over-expression targets RAF1 kinase domain-GFP to mitochondria
mitochondria-targeted RAF1 (deleted for Ras binding domain) potentiates BCL2 anti-apoptotic activity in 32D.3 exposed to staurosporine or upon IL-3 withdrawal

Modifications:
Participates in complexes:
In compartment: Mitochondrial inner membrane
  1. BAD|​S91_unk:​BCL2@Mitochondrial inner membrane map
Participates in reactions:
As Reactant or Product:
  1. BAD|​S91_unk:​BCL2@Mitochondrial inner membrane map → map BCL2@Mitochondrial inner membrane map + BAD|​pho@Cytosol map
  2. BAD|​S91_unk|​active@Mitochondrial inner membrane map + BCL2|​pho@Mitochondrial inner membrane map → map BAD|​S91_unk:​BCL2@Mitochondrial inner membrane map
As Catalyser: