Simple molecule hyaluronan map
hyaluronan@Cytosol

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / MATRIX_REGULATION  map

References
PMID:20823158
CAFs have been identified as a source of hyaluronan, and genetic ablation of the hyaluronan synthase gene (Has2) in fibroblasts strongly diminishes the entry of macrophages into the tumour microenvironment.

hyaluronan@default

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / MATRIX_REGULATION  map

References
PMID:20823158
CAFs have been identified as a source of hyaluronan, and genetic ablation of the hyaluronan synthase gene (Has2) in fibroblasts strongly diminishes the entry of macrophages into the tumour microenvironment.

Modifications:
In compartment: Cytosol
  1. hyaluronan@Cytosol map
In compartment: default
  1. hyaluronan@default map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. hyaluronan@Cytosol map → map hyaluronan@default map
    2. hyaluronan@default map → map ECM_REGULATION@default map
    As Catalyser: