Protein ACER* map

Identifiers
alkaline ceramidase 1
HUGO:ACER1 HGNC:18356 ENTREZ:125981 UNIPROT:Q8TDN7

Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / MITOCHONDRIAL_METABOLISM  map
 Regulated Cell Death  map  / NECROPTOSIS  map

References
PMID:16716889
Nitric oxide (NO) is known to activate N-ceramidase degradation through the ubiquitine/proteasome pathway.

ACER*@Cytosol

Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / MITOCHONDRIAL_METABOLISM  map
 Regulated Cell Death  map  / NECROPTOSIS  map

References
rc_re1567( Regulated Cell Death  map ):
PMID:10792026
Nitric oxide inhibits tumor necrosis factor-alpha-induced apoptosis by reducing the generation of ceramide.

ACER*|​ubi@Cytosol

Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / MITOCHONDRIAL_METABOLISM  map
 Regulated Cell Death  map  / NECROPTOSIS  map

References
rc_re1567( Regulated Cell Death  map ):
PMID:10792026
Nitric oxide inhibits tumor necrosis factor-alpha-induced apoptosis by reducing the generation of ceramide.

Modifications:
In compartment: Cytosol
  1. ACER*@Cytosol map
  2. ACER*|​ubi@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. ACER*@Cytosol map → map ACER*|​ubi@Cytosol map
    2. ACER*|​ubi@Cytosol map → map degraded
    3. ACER1@Cytosol map → map ACER*@Cytosol map
    4. ACER2@Cytosol map → map ACER*@Cytosol map
    5. ACER3@Cytosol map → map ACER*@Cytosol map
    As Catalyser:
    1. Ceramide@Cytosol map + H2O@Cytosol map → map Sphingosine@Cytosol map + Carboxylate@Cytosol map