Protein GALNT14 map

Identifiers
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
HUGO:GALNT14 HGNC:22946 ENTREZ:79623 UNIPROT:Q96FL9

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / TRAIL_RESPONSE  map
 RECON2  map

References
PMID:20531300
24 peptidyl GalNAc transferase(GALNT) isoforms activation lead to trimerization of DR4/5 receptors

GALNT14@Cytosol

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / TRAIL_RESPONSE  map

References
rc_re1640( Regulated Cell Death  map ):
PMID:19090789
Palmitoylation of the TRAIL receptor DR4 confers an efficient TRAIL-induced cell death signalling
PMID:17767167
Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL.
PMID:10894161
Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5
PMID:28258062
The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death.

Modifications:
In compartment: Cytosol
  1. GALNT14@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
      As Catalyser:
      1. DR4/5*:​TRAIL*@Cytosol map + FADD@Cytosol map → map rc_s5142