Protein SMUG map

Identifiers
single-strand-selective monofunctional uracil-DNA glycosylase 1
HUGO:SMUG, HGNC:17148, ENTREZ:23583, UNIPROT:Q53HV7

Maps_Modules
HMC:GENOME_INSTABILITY_AND_MUTATION
 Cell Cycle DNA Repair  map  / BER  map

References
PMID:15703371, PMID:19847258, PMID:16697054

SMUG@Nucleus

References
ce_re5( Cell Cycle DNA Repair  map ):
9-1-1 complex activates TDG glycosylase and activates BER:
PMID:17855402
DNA with O6-methylguanine adducts, MutSalpha and MutLalpha activate ATR/ATRIP and BER pathways performs the repair:
PMID:16713580, PMID:18543256

Modifications:
In compartment: Nucleus
  1. SMUG@Nucleus map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
      As Catalyser:
      1. gDeaminated_alkylated_mismatched_base*@Nucleus map → map gBER_M-glyc_DNA_st2*@Nucleus map + Base@Nucleus map